Inhibition of leukopoiesis by sera from Trypanosoma congolense infected calves: partial characterization of the inhibitory factor. Academic Article uri icon

abstract

  • Sera collected from calves infected with Trypanosoma congolense inhibited bovine granulocyte/macrophage colony formation in vitro, but not erythroid colony formation. The inhibitor was found to be TCA precipitable in nature and on Sephadex G-200 chromatography, it was found to elute with the second major peak. Sonicated T. brucei, T. congolense, and T. theileri added directly into the cultures had no effect on granulocyte/macrophage colony formation, but induced significant enhancement of erythroid colony formation.

published proceedings

  • Tropenmed Parasitol

author list (cited authors)

  • Kaaya, G. P., Tizard, I. R., Maxie, M. G., & Valli, V. E.

citation count

  • 8

complete list of authors

  • Kaaya, GP||Tizard, IR||Maxie, MG||Valli, VE

publication date

  • June 1980