Studies of the effect of acemannan on retrovirus infections: clinical stabilization of feline leukemia virus-infected cats. Academic Article

abstract

• Feline leukemia is a disease induced by an oncornavirus infection that inevitably causes clinically affected cats to die. It has been estimated that 40% of cats are dead within 4 weeks and 70% within 8 weeks of the onset of clinical symptoms. Acemannan is a complex carbohydrate with both immunostimulatory and direct antiviral properties. Administration of acemannan for 6 weeks intraperitoneally to clinically symptomatic cats significantly improved both the quality of life and the survival rate. Twelve weeks after initiation of treatment, 71% of treated cats were alive and in good health.

authors

• Tizard, Ian

published proceedings

• Mol Biother

author list (cited authors)

• Sheets, M. A., Unger, B. A., Giggleman, G. F., & Tizard, I. R.

citation count

• 43

complete list of authors

• Sheets, MA||Unger, BA||Giggleman, GF||Tizard, IR

publication date

• March 1991

published in

• Molecular biotherapy  Journal

keywords

• Adjuvants, Immunologic
• Animals
• Cat Diseases
• Cats
• Injections, Intraperitoneal
• Leukemia
• Leukemia Virus, Feline
• Mannans

PubMed Central ID

• 1648929

start page

• 41

end page

• 45

volume

• 3

issue

• 1