Inhibition of pathogenicity of the rice blast fungus by Saccharomyces cerevisiae alpha-factor. Academic Article

abstract

• Magnaporthe grisea is a fungal pathogen with two mating types, MAT1-1 and MAT1-2, that forms a specialized cell necessary for pathogenesis, the appressorium. Saccharomyces cerevisiae alpha-factor pheromone blocked appressorium formation in a mating type-specific manner and protected plants from infection by MAT1-2 strains. Experiments with alpha-factor analogs suggest that the observed activity is due to a specific interaction of alpha-factor with an M. grisea receptor. Culture filtrates of a MAT1-1 strain contained an activity that inhibited appressorium formation of mating type MAT1-2 strains. These findings provide evidence that a pheromone response pathway exists in M. grisea that can be exploited for plant protection.

authors

• Ebbole, Daniel

published proceedings

• Science

altmetric score

• 3.25

author list (cited authors)

• Beckerman, J. L., Naider, F., & Ebbole, D. J.

citation count

• 47

complete list of authors

• Beckerman, JL||Naider, F||Ebbole, DJ

publication date

• May 1997

publisher

• American Association for the Advancement of Science (AAAS)  Publisher

published in

• Science  Journal

keywords

• Amino Acid Sequence
• Ascomycota
• Crosses, Genetic
• Cyclic AMP
• Hordeum
• Mating Factor
• Molecular Sequence Data
• Oryza
• Peptides
• Pheromones
• Plant Diseases
• Receptors, Mating Factor
• Receptors, Peptide
• Saccharomyces Cerevisiae
• Transcription Factors

PubMed Central ID

• 9148806

Digital Object Identifier (DOI)

• 10.1126/science.276.5315.1116

start page

• 1116

end page

• 1119

volume

• 276

issue

• 5315

URL

• http%3A%2F%2Fdx.doi.org%2F10.1126%2Fscience.276.5315.1116