Seroprevalence and molecular evidence for the presence of bovine immunodeficiency virus in Brazilian cattle. Academic Article uri icon


  • Data on the worldwide distribution of bovine immunodeficiency virus (BIV) and bovine leukemia virus (BLV) is limited. A prevalence study of antibodies to BIV and BLV was conducted in six different cattle herds in Brazil. Out of a total of 238 sera analyzed, 11.7% were found positive for anti-BIV p26 antibodies as determined by Western blot analysis, 2.1% were positive for anti-BLV gp51 antibodies as detected by immunodiffusion test. Peripheral blood mononuclear cells from BIV seropositive cattle were found to have BIV-provirus DNA, as detected by nested polymerase chain reaction. A nucleotide sequence corresponding to a 298 bp fragment of the BIV pol gene was also analyzed. Amino acid sequences of these Brazilian pol gene products showed 98.0 to 100% homology to the American strain BIV R29, 97.0 to 99.0% to Japanese BIV isolates, and divergence ranged from 0 to 4.0% among Brazilian BIV isolates. This evidence of the presence of BIV and BLV infections in Brazil should be considered a health risk to Brazilian cattle populations and a potential causative agent of chronic disease in cattle.

published proceedings

  • Jpn J Vet Res

author list (cited authors)

  • Meas, S., Ruas, J., Farias, N. A., Usui, T., Teraoka, Y., Mulenga, A., ... Onuma, M.

citation count

  • 12

complete list of authors

  • Meas, Sothy||Ruas, Jeronimo||Farias, Nara Amelia||Usui, Tatsufumi||Teraoka, Yoshiyuki||Mulenga, Albert||Chang, Kyung-Soo||Masuda, Aoi||Madruga, Claudo Roberto||Ohashi, Kazuhiko||Onuma, Misao

publication date

  • May 2002