Preparation of [ 18 F]-NHC-BF 3 conjugates and their applications in PET imaging Academic Article uri icon

abstract

  • © The Royal Society of Chemistry. N-Heterocyclic carbene boron trifluoride (NHC-BF3) conjugates were successfully radiofluorinated by SnCl4-promoted 18F-19F isotopic exchange reaction in one labelling step. This method afforded in vivo stable PET agents that efficiently bound to targeted tumours yielding PET images with good tumour-to-background contrast.

altmetric score

  • 2.85

author list (cited authors)

  • Chansaenpak, K., Wang, M., Wang, H., Giglio, B. C., Gabbaï, F. P., Wu, Z., & Li, Z.

citation count

  • 6

publication date

  • January 2017