Identification of a Plasmid-Mediated Quinolone Resistance Gene in Salmonella Isolates from Texas Dairy Farm Environmental Samples. Academic Article

abstract

• A recent increase in plasmid-mediated quinolone resistance (PMQR) has been detected among Salmonella isolated from humans in the United States, and it is necessary to determine the sources of human infection. We had previously isolated Salmonella from dairy farm environmental samples collected in Texas, and isolates were tested for anti-microbial susceptibility. Two isolates, serotyped as Salmonella Muenster, showed the discordant pattern of nalidixic acid susceptibility and intermediate susceptibility to ciprofloxacin. For this project, whole-genome sequencing of both isolates was performed to detect genes associated with quinolone resistance. The plasmid-mediated qnrB19 gene and IncR plasmid type were identified in both isolates. To our knowledge, this is the first report of PMQR in Salmonella isolated from food animals or agricultural environments in the United States.

authors

• Norman, Keri
• Scott, Harvey

published proceedings

• Zoonoses Public Health

altmetric score

• 0.5

author list (cited authors)

• Cummings, K. J., Rodriguez-Rivera, L. D., Norman, K. N., Ohta, N., & Scott, H. M.

citation count

• 10

complete list of authors

• Cummings, KJ||Rodriguez-Rivera, LD||Norman, KN||Ohta, N||Scott, HM

publication date

• June 2017

publisher

• Wiley  Publisher

published in

• Zoonoses and Public Health  Journal

keywords

• Animals
• Antimicrobial Resistance
• Cattle
• Cattle Diseases
• Dairy Cattle
• Dairying
• Drug Resistance, Bacterial
• Environmental Microbiology
• Farms
• Foodborne Disease
• Humans
• Public Health
• Quinolones
• R Factors
• Salmonella
• Salmonella Infections, Animal
• Salmonella Spp
• Texas
• Zoonoses

PubMed Central ID

• 27801549

Digital Object Identifier (DOI)

• 10.1111/zph.12318

start page

• 305

end page

• 307

volume

• 64

issue

• 4

URL

• http://dx.doi.org/10.1111/zph.12318