Canine and Human Atopic Dermatitis: Two Faces of the Same Host-Microbe Interaction
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Host-microbe interaction has been suggested to play a critical role in the pathogenesis of atopic dermatitis. The dog has been shown to be the best model to study both pathogenesis and microbiome modifications in atopic dermatitis. Bradley et al. show a significant correlation between microbiome diversity, clinical signs, and skin barrier function in atopic dogs before, during, and after antimicrobial therapy.
author list (cited authors)
Santoro, D., & Hoffmann, A. R.