The nuclear pore complex: a protein machine bridging the nucleus and cytoplasm. Academic Article

abstract

• Compositional analysis of nuclear pore complexes (NPCs) is nearing completion, and efforts are now focused on understanding how these protein machines work. Recent analysis of soluble transport factor interactions with NPC proteins reveals distinct and overlapping pathways for movement between the nucleus and cytoplasm. New fluorescence- and microscopy-based strategies have been used to monitor the pathway of NPC assembly and to reveal the dynamics of the NPC during transport.

authors

• Ryan, Kathryn

published proceedings

• Curr Opin Cell Biol

altmetric score

• 3

author list (cited authors)

• Ryan, K. J., & Wente, S. R.

citation count

• 215

complete list of authors

• Ryan, KJ||Wente, SR

publication date

• January 2000

publisher

• Elsevier  Publisher

published in

• Current Opinion in Cell Biology  Journal

keywords

• Animals
• Biological Transport, Active
• Cell Nucleus
• Cytoplasm
• Humans
• Mitosis
• Nuclear Envelope
• Nuclear Proteins
• Protein Conformation
• RNA, Messenger
• Saccharomyces Cerevisiae

Digital Object Identifier (DOI)

• 10.1016/s0955-0674(00)00101-0

start page

• 361

end page

• 371

volume

• 12

issue

• 3

URL

• http%3A%2F%2Fdx.doi.org%2F10.1016%2Fs0955-0674%2800%2900101-0