Growth Factors and Signaling Proteins in Craniofacial Development Academic Article

abstract

• Regulation of growth and development is controlled by the interactions of cells with each other and the extracellular environment through signal transduction pathways that control the differentiation process by stimulating proliferation or causing cell death. This review will define the common signaling molecules and provide an overview of the general principles of signal transduction events. We also review the signal transduction pathways controlling one specific mechanism found in craniofacial development termed epithelial-mesenchymal transformation (EMT) employed during gastrulation, cranial neural crest migration, and secondary palate formation. 2005 Elsevier Inc. All rights reserved.

authors

• Svoboda, Kathy

published proceedings

• Seminars in Orthodontics

author list (cited authors)

• Spears, R., & Svoboda, K.

citation count

• 7

complete list of authors

• Spears, Robert||Svoboda, Kathy KH

publication date

• January 2005

publisher

• Elsevier  Publisher

published in

• Seminars in Orthodontics  Journal

keywords

• 1 Underpinning Research
• 1.1 Normal Biological Development And Functioning
• Biotechnology
• Cancer
• Congenital Structural Anomalies
• Dental/oral And Craniofacial Disease
• Generic Health Relevance
• Pediatric

Digital Object Identifier (DOI)

• 10.1053/j.sodo.2005.07.003

start page

• 184

end page

• 198

volume

• 11

issue

• 4

URL

• http%3A%2F%2Fdx.doi.org%2F10.1053%2Fj.sodo.2005.07.003