Cellular response to force application at craniofacial sutures Academic Article

abstract

• Objectives - To provide a comprehensive review of the literature describing research done on the responses of suture cells to force application in vitro and in vivo. Design and Results: This review outlines the types of forces that can be applied, methods of applying the forces, the sutures used in experiments, and the changes in morphology, molecular biology (gene and protein expression), and cell biology (proliferation, differentiation, apoptosis) in response to these forces. Conclusion: The molecular response of sutures to force needs to be further investigated as these molecules can be used to enhance the way in which craniofacial sutures respond to mechanical force during orthopedic-orthodontic treatment. 2006 The Authors.

authors

• Opperman, Lynne

published proceedings

• Orthodontics and Craniofacial Research

author list (cited authors)

• Alaqeel, S. M., Hinton, R. J., & Opperman, L. A.

citation count

• 26

complete list of authors

• Alaqeel, SM||Hinton, RJ||Opperman, LA

publication date

• August 2006

publisher

• Wiley  Publisher

published in

• Orthodontics and Craniofacial Research  Journal

keywords

• Apoptosis
• Bioengineering
• Cell Differentiation
• Cell Proliferation
• Cells, Cultured
• Cranial Sutures
• Dental/oral And Craniofacial Disease
• Gene Expression
• Humans
• Pediatric
• Pediatric Research Initiative
• Protein Biosynthesis
• Stress, Mechanical

Digital Object Identifier (DOI)

• 10.1111/j.1601-6343.2006.00371.x

start page

• 111

end page

• 122

volume

• 9

issue

• 3

URL

• http%3A%2F%2Fdx.doi.org%2F10.1111%2Fj.1601-6343.2006.00371.x