Agrin isoforms and their role in synaptogenesis. Academic Article

abstract

• Agrin is thought to mediate the motor neuron-induced aggregation of synaptic proteins on the surface of muscle fibers at neuromuscular junctions. Recent experiments provide direct evidence in support of this hypothesis, reveal the nature of agrin immunoreactivity at sites other than neuromuscular junctions, and have resulted in findings that are consistent with the possibility that agrin plays a role in synaptogenesis throughout the nervous system.

authors

• Mcmahan, Uel

published proceedings

• Curr Opin Cell Biol

author list (cited authors)

• McMahan, U. J., Horton, S. E., Werle, M. J., Honig, L. S., Krger, S., Ruegg, M. A., & Escher, G.

citation count

• 133

complete list of authors

• McMahan, UJ||Horton, SE||Werle, MJ||Honig, LS||Kröger, S||Ruegg, MA||Escher, G

publication date

• January 1992

publisher

• Elsevier  Publisher

published in

• Current Opinion in Cell Biology  Journal

keywords

• Agrin
• Amino Acid Sequence
• Animals
• Humans
• Molecular Sequence Data
• Motor Neurons
• Nerve Tissue Proteins
• Synapses

Digital Object Identifier (DOI)

• 10.1016/0955-0674(92)90113-q

start page

• 869

end page

• 874

volume

• 4

issue

• 5

URL

• http%3A%2F%2Fdx.doi.org%2F10.1016%2F0955-0674%2892%2990113-q