Electric Field-Based Organization of Cytoskeletal Nanowires Using Metallic Glass Wire Electrodes**Research supported by the World Premier International Research Center Initiative (WPI), MEXT, Japan.
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© 2016 IEEE. We present electric field-based in-vitro control of intracellular protein nanowires, so-called microtubules, using a pair of metallic glass (Pd42.5Cu30Ni7.5P20) microwire electrodes. We can reversibly control the spatio-temporal localization, orientation, as well as guided translocation of microtubules suspended in a buffer solution. Using freestanding wire electrodes to localize microtubules allows for an assembly of nanowires in a 0 or 1-dimensional environment, with the potential of producing more complex geometries. This is of particular interest where bio-mimetic applications require control beyond planar devices.
author list (cited authors)
Kim, K., Nakayama, K. S., Umetsu, M., Hwang, W., & Teizer, W.