Gene expression-based glioma classification using hierarchical Bayesian Vector machines Academic Article uri icon

abstract

  • This paper considers several Bayesian classification methods for the analysis of the glioma cancer with microarray data based on reproducing kernel Hilbert space under the multiclass setup. We consider the multinomial logit likelihood as well as the likelihood related to the multiclass Support Vector Machine (SVM) model. It is shown that our proposed Bayesian classification models with multiple shrinkage parameters can produce more accurate classification scheme for the glioma cancer compared to several existing classical methods. We have also proposed a Bayesian variable selection scheme for selecting the differentially expressed genes integrated with our model. This integrated approach improves classifier design by yielding simultaneous gene selection. 2007, Indian Statistical Institute.

published proceedings

  • Sankhya: The Indian Journal of Statistics

author list (cited authors)

  • Chakraborty, S., Mallick, B. K., Ghosh, D., Ghosh, M., & Doughertry, E.

complete list of authors

  • Chakraborty, S||Mallick, BK||Ghosh, D||Ghosh, M||Doughertry, E

publication date

  • December 2007