Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis. Academic Article uri icon


  • Draft genome sequences have been determined for the soybean pathogen Phytophthora sojae and the sudden oak death pathogen Phytophthora ramorum. Omycetes such as these Phytophthora species share the kingdom Stramenopila with photosynthetic algae such as diatoms, and the presence of many Phytophthora genes of probable phototroph origin supports a photosynthetic ancestry for the stramenopiles. Comparison of the two species' genomes reveals a rapid expansion and diversification of many protein families associated with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors, and, in particular, a superfamily of 700 proteins with similarity to known omycete avirulence genes.

published proceedings

  • Science

altmetric score

  • 6.25

author list (cited authors)

  • Tyler, B. M., Tripathy, S., Zhang, X., Dehal, P., Jiang, R., Aerts, A., ... Boore, J. L.

citation count

  • 858

complete list of authors

  • Tyler, Brett M||Tripathy, Sucheta||Zhang, Xuemin||Dehal, Paramvir||Jiang, Rays HY||Aerts, Andrea||Arredondo, Felipe D||Baxter, Laura||Bensasson, Douda||Beynon, Jim L||Chapman, Jarrod||Damasceno, Cynthia MB||Dorrance, Anne E||Dou, Daolong||Dickerman, Allan W||Dubchak, Inna L||Garbelotto, Matteo||Gijzen, Mark||Gordon, Stuart G||Govers, Francine||Grunwald, Niklaus J||Huang, Wayne||Ivors, Kelly L||Jones, Richard W||Kamoun, Sophien||Krampis, Konstantinos||Lamour, Kurt H||Lee, Mi-Kyung||McDonald, W Hayes||Medina, Mónica||Meijer, Harold JG||Nordberg, Eric K||Maclean, Donald J||Ospina-Giraldo, Manuel D||Morris, Paul F||Phuntumart, Vipaporn||Putnam, Nicholas H||Rash, Sam||Rose, Jocelyn KC||Sakihama, Yasuko||Salamov, Asaf A||Savidor, Alon||Scheuring, Chantel F||Smith, Brian M||Sobral, Bruno WS||Terry, Astrid||Torto-Alalibo, Trudy A||Win, Joe||Xu, Zhanyou||Zhang, Hongbin||Grigoriev, Igor V||Rokhsar, Daniel S||Boore, Jeffrey L

publication date

  • September 2006