CRITICAL BOOLEAN NETWORKS REQUIRE MINIMAL INTERVENTION RATE Conference Paper uri icon

abstract

  • A prime objective of modeling gene regulatory networks is the identification of potential targets for therapeutic intervention. To this end, it is crucial to understand the structure-dynamics relationships in biological networks. In this work, we investigate the relationship between the structure ofgene regulatory networks modeled as Boolean networks and the benefit-to-intervention-rate ratio of optimal intervention strategies derived for them.

name of conference

  • 2009 IEEE International Workshop on Genomic Signal Processing and Statistics

published proceedings

  • 2009 IEEE International Workshop on Genomic Signal Processing and Statistics

author list (cited authors)

  • Vahedi, G., Shmulevich, I., Liu, W., & Dougherty, E.

citation count

  • 0

complete list of authors

  • Vahedi, Golnaz||Shmulevich, Ilya||Liu, Wenbin||Dougherty, Edward

publication date

  • May 2009