Labeling of Polymer Nanostructures for Medical Imaging: Importance of crosslinking extent, spacer length, and charge density. Academic Article

abstract

• Radiolabeling studies were employed to investigate the influence of structure on the efficiency of surface functionalization for poly(acrylic acid)-coated shell crosslinked nanoparticles (SCKs) with two types of amine-terminated DOTA chelators. An intricate interplay between the chemical and physical properties of both the DOTA derivative and the SCK nanostructures was revealed, demonstrating the importance of structural control.

authors

• Wooley, Karen

published proceedings

• Macromolecules

altmetric score

• 6

author list (cited authors)

• Xu, J., Sun, G., Rossin, R., Hagooly, A., Li, Z., Fukukawa, K., ... Wooley, K. L.

citation count

• 42

complete list of authors

• Xu, Jinqi||Sun, Guorong||Rossin, Raffaella||Hagooly, Aviv||Li, Zicheng||Fukukawa, Ken-Ichi||Messmore, Benjamin W||Moore, Dennis A||Welch, Michael J||Hawker, Craig J||Wooley, Karen L

publication date

• May 2007

publisher

• American Chemical Society (ACS)  Publisher

published in

• MACROMOLECULES  Journal

keywords

• 34 Chemical Sciences
• 3403 Macromolecular And Materials Chemistry
• 40 Engineering
• Bioengineering
• Nanotechnology

PubMed Central ID

• 18779874

Digital Object Identifier (DOI)

• 10.1021/ma070267j

start page

• 2971

end page

• 2973

volume

• 40

issue

• 9

URL

• http%3A%2F%2Fdx.doi.org%2F10.1021%2Fma070267j