Shell crosslinked knedel-like nanoparticles for delivery of cisplatin: effects of crosslinking
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Polymeric micelles and shell crosslinked knedel-like (SCK) nanoparticles were loaded with up to 48% (w/w) cisplatin. These spherical cisplatin-loaded nanoparticles displayed sustained platinum release over 5 days in PBS, enhanced stability over free cisplatin in aqueous milieu, and significant antitumor activity in vitro against two cancer cell lines.
author list (cited authors)
Zhang, F., Elsabahy, M., Zhang, S., Lin, L. Y., Zou, J., & Wooley, K. L.