The advantages of nanoparticles for PET. Academic Article

abstract

• Nanoparticles have an advantage for molecular imaging in that many functionalities can be added to the surface and interior of the particle. This brief review focuses on the design of nanomaterials that take advantage of PET. An evolutionary approach is presented, leading to the optimization of the nanoparticle composition and structure to achieve controlled in vivo circulation and tissue-selective targeting. Organic and inorganic nanostructures are included. Nanoprobes for PET of angiogenesis and cancer are highlighted.

authors

• Wooley, Karen

published proceedings

• J Nucl Med

author list (cited authors)

• Welch, M. J., Hawker, C. J., & Wooley, K. L.

citation count

• 113

complete list of authors

• Welch, Michael J||Hawker, Craig J||Wooley, Karen L

publication date

• November 2009

publisher

• Society of Nuclear Medicine  Publisher

published in

• JOURNAL OF NUCLEAR MEDICINE  Journal

keywords

• Animals
• Integrin AlphaVbeta3
• Mice
• Nanoparticles
• Polymers
• Positron-Emission Tomography
• Rats
• Tissue Distribution

PubMed Central ID

• 19837751

Digital Object Identifier (DOI)

• 10.2967/jnumed.109.061846

start page

• 1743

end page

• 1746

volume

• 50

issue

• 11

URL

• http%3A%2F%2Fdx.doi.org%2F10.2967%2Fjnumed.109.061846