Construction of a versatile and functional nanoparticle platform derived from a helical diblock copolypeptide-based biomimetic polymer. Academic Article uri icon


  • Sequential polymerization of N-carboxyanhydrides accelerated by nitrogen flow is utilized to generate a novel well-defined diblock copolypeptide (PDI = 1.08), with incorporation of alkyne-functionalized side-chain groups allowing for rapid and efficient thiol-yne click-type modifications, followed by self-assembly into nanopure water to construct a helical polypeptide-based versatile and functional nanoparticle platform.

published proceedings

  • Polym Chem

altmetric score

  • 0.5

author list (cited authors)

  • Fan, J., Li, R., He, X., Seetho, K., Zhang, F., Zou, J., & Wooley, K. L.

citation count

  • 21

complete list of authors

  • Fan, Jingwei||Li, Richen||He, Xun||Seetho, Kellie||Zhang, Fuwu||Zou, Jiong||Wooley, Karen L

publication date

  • July 2014