Construction of a versatile and functional nanoparticle platform derived from a helical diblock copolypeptide-based biomimetic polymer. Academic Article

abstract

• Sequential polymerization of N-carboxyanhydrides accelerated by nitrogen flow is utilized to generate a novel well-defined diblock copolypeptide (PDI = 1.08), with incorporation of alkyne-functionalized side-chain groups allowing for rapid and efficient thiol-yne click-type modifications, followed by self-assembly into nanopure water to construct a helical polypeptide-based versatile and functional nanoparticle platform.

authors

• Wooley, Karen

published proceedings

• Polym Chem

altmetric score

• 0.5

author list (cited authors)

• Fan, J., Li, R., He, X., Seetho, K., Zhang, F., Zou, J., & Wooley, K. L.

citation count

• 21

complete list of authors

• Fan, Jingwei||Li, Richen||He, Xun||Seetho, Kellie||Zhang, Fuwu||Zou, Jiong||Wooley, Karen L

publication date

• July 2014

publisher

• Royal Society of Chemistry (RSC)  Publisher

published in

• Polymer Chemistry  Journal

keywords

• 34 Chemical Sciences
• 3403 Macromolecular And Materials Chemistry
• Bioengineering
• Nanotechnology

PubMed Central ID

• 25013459

Digital Object Identifier (DOI)

• 10.1039/C4PY00628C

start page

• 3977

end page

• 3981

volume

• 5

issue

• 13

URL

• http%3A%2F%2Fdx.doi.org%2F10.1039%2Fc4py00628c