REDOR determination of the composition of shell cross-linked amphiphilic core-shell nanoparticles and the partitioning of sequestered fluorinated guests

abstract

• Rotational-echo double-resonance (REDOR) 13C{19F} and 15N{19F} NMR spectra have been obtained for guest-host complexes of 6-fluorotryptophan and 4-(trifluoromethyl)benzophenone with polymeric amphiphilic nanoparticles, consisting of a polystyrene core covalently attached to a poly(acrylic acid)-co-[15N]polyacrylamide shell. The REDOR spectra were used both to determine the composition of the nanoparticles and to find the locations of the fluorinated guests. Each guest resides near the core-shell interface of the nanoparticle, with the hydrophobic 4-(trifluoromethyl)benzophenone within the core and the amphiphilic 6-fluorotryptophan within the shell.

authors

• Wooley, Karen

published proceedings

• MACROMOLECULES

author list (cited authors)

• Huang, H. Y., Wooley, K. L., & Schaefer, J.

citation count

• 31

complete list of authors

• Huang, HY||Wooley, KL||Schaefer, J

publication date

• January 2001

publisher

• American Chemical Society (ACS)  Publisher

published in

• MACROMOLECULES  Journal

keywords

• 34 Chemical Sciences
• 3403 Macromolecular And Materials Chemistry
• Bioengineering
• Nanotechnology

Digital Object Identifier (DOI)

• 10.1021/ma001003z

start page

• 547

end page

• 551

volume

• 34

issue

• 3

URL

• https://doi.org/10.1021/ma001003z