Fundamental design aspects of amphiphilic shell-crosslinked nanoparticles for controlled release applications Academic Article uri icon

abstract

  • A unique method is developed for the controlled release of the hydrophobic polymer chains from the core of the shell crosslinked nanoparticles (SCKs) by selective cleavage of labile C-ON bonds present at the core-shell interface; this represents a methodology to probe the permeability of nanoscopic membranes and a means for applications in the controlled release of macromolecular species.

author list (cited authors)

  • Murthy, K. S., Ma, Q., Clark, C. G., Remsen, E. E., & Wooley, K. L.

citation count

  • 61

publication date

  • January 2001