A Study of Ion-Neutral Collision Cross Section Values for Low Charge States of Peptides, Proteins, and Peptide/Protein Complexes. Academic Article

abstract

• Here, we report ion-helium collision cross sections (CCS) for a number of peptide, small protein, and peptide/protein ionic complexes. The CCS values reported here are compared to previously reported results.[1, 2] We also compare values for low charge state species, i.e., [M + H](+) and [M + 2H](2+), formed by MALDI with values for high charge state species formed by ESI, and the measured CCSs are compared with predicted CCS for solid-state and solution phase structures and calculated structures obtained by using a protein-protein structure algorithm generator, based on a combined Biomolecular complex Generation with Global Evaluation and Ranking[3] and Multi Dimensional Scaling[4].

authors

• Russell, David

published proceedings

• Int J Mass Spectrom

altmetric score

• 3

author list (cited authors)

• Fernandez-Lima, F. A., Blase, R. C., & Russell, D. H.

citation count

• 38

complete list of authors

• Fernandez-Lima, Francisco A||Blase, Ryan C||Russell, David H

publication date

• December 2010

publisher

• Elsevier  Publisher

published in

• International Journal of Mass Spectrometry  Journal

keywords

• Cluster Analysis
• Ion Mobility Spectrometry
• Ion-helium Collision Cross-section
• Peptide And Protein Complex Secondary Structure
• Protein Docking
• Protein Oligomers

PubMed Central ID

• 21503273

Digital Object Identifier (DOI)

• 10.1016/j.ijms.2009.10.009

start page

• 111

end page

• 118

volume

• 298

issue

• 1-3

URL

• http://dx.doi.org/10.1016/j.ijms.2009.10.009