A novel surface-induced dissociation instrument for ion mobility-time-of-flight mass spectrometry Academic Article

abstract

• A surface-normal surface-induced dissociation (SID) configuration specifically designed for coupling ion mobility spectrometry (IMS) and orthogonal time-of-flight (TOF) mass spectrometer is described. The instrument configuration and the effects of various operating parameters are critically evaluated using ion trajectory calculations (SIMION) and SID spectra of a series of model peptides. The utility of the instrument configuration for simultaneous acquisition of MS and MS-MS spectra in both data-dependent and non-data-dependent modes are also discussed. 2006 Elsevier B.V. All rights reserved.

authors

• Russell, David

published proceedings

• INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

author list (cited authors)

• Sun, W., May, J. C., & Russell, D. H.

citation count

• 26

complete list of authors

• Sun, Wenjian||May, Jody C||Russell, David H

publication date

• January 2007

publisher

• Elsevier  Publisher

published in

• International Journal of Mass Spectrometry  Journal

keywords

• Ion Mobility
• Matrix Assisted Laser Desorption/ionization
• Surface-induced Dissociation
• Time-of-flight

Digital Object Identifier (DOI)

• 10.1016/j.ijms.2006.09.005

start page

• 79

end page

• 86

volume

• 259

issue

• 1-3

URL

• http://dx.doi.org/10.1016/j.ijms.2006.09.005