Fast atom bombardment--tandem mass spectrometry studies of organo-alkali metal ions of small peptides.

abstract

• Tandem mass spectrometry (TMS) combined with fast-atom bombardment (FAB) ionization is potentially useful for the structural characterization of blomolecules. The advantages of the FAB-TMS experiment have been discussed in previous works, with the major advantages usually relating to mixture analysis. In this work, FAB-TMS is used to study the dissociation reactions of the [M + H]+ and [M + Na]+ ions of a small peptide, i.e., hippuryl-L-histidyl-L-leucine. This work shows that additional information can be gained by comparing the dissociation reactions of these two different ionic forms. Owing to the specific binding of Na+ in the organo-alkail metal ion, the collision-induced dissociation spectrum of the [M + Na]+ ion of hippuryi-L-histidyl-L-leucine shows characteristic dissociation reactions not observed for the [M + H]+ ion. 1986, American Chemical Society. All rights reserved.

authors

• Russell, David

published proceedings

• Anal Chem

author list (cited authors)

• Mallis, L. M., & Russell, D. H.

citation count

• 106

complete list of authors

• Mallis, LM||Russell, DH

publication date

• May 1986

publisher

• American Chemical Society (ACS)  Publisher

published in

• Analytical Chemistry  Journal

keywords

• Ions
• Mass Spectrometry
• Metals
• Peptides

PubMed Central ID

• 3717572

Digital Object Identifier (DOI)

• 10.1021/ac00297a021

start page

• 1076

end page

• 1080

volume

• 58

issue

• 6

URL

• https://doi.org/10.1021/ac00297a021