Detection of femtomole and sub-femtomole levels of peptides by tandem magnetic sector/reflectron time-of-flight mass spectrometry and matrix-assisted laser desorption ionization. Academic Article uri icon

abstract

  • This article describes results of low-level (sub-femtomole) detection of peptides by matrix-assisted laser desorption ionization. The matrix-assisted laser desorption ionization method can be used for low-level detection of the parent ion, either [M + H](+) or [M + Na](+), and collision-induced dissociation of the parent ion can be performed at the picomole level. The instrument used for these studies is a novel high-performance magnetic sector (electric(E)/magnetic(B) sector)/reflectron time-of-flight (TOP) tandem mass spectrometer (EB/TOF).

published proceedings

  • J Am Soc Mass Spectrom

altmetric score

  • 3

author list (cited authors)

  • Strobel, F. H., Solouki, T., White, M. A., & Russell, D. H.

citation count

  • 51

complete list of authors

  • Strobel, FH||Solouki, T||White, MA||Russell, DH

publication date

  • January 1991