A dual time-of-flight apparatus for an ion mobility-surface-induced dissociation-mass spectrometer for high-throughput peptide sequencing Academic Article

abstract

• A novel ion mobility (IM)-surface-induced dissociation (SID)-mass spectrometer consisting of two independent time-of-flight (TOF) mass analyzers is described. The dual TOF instrument configuration facilitates high-throughput post-ionization separation and mass analysis of precursor and fragment ions, and the utility of 3D data acquisition is demonstrated for top-down proteomics by performing simultaneous acquisition of peptide mass maps and amino acid sequence determination. 2008 Elsevier B.V. All rights reserved.

authors

• Russell, David

published proceedings

• INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

author list (cited authors)

• Sun, W., May, J. C., Gillig, K. J., & Russell, D. H.

citation count

• 9

complete list of authors

• Sun, Wenjian||May, Jody C||Gillig, Kent J||Russell, David H

publication date

• October 2009

publisher

• Elsevier  Publisher

published in

• International Journal of Mass Spectrometry  Journal

keywords

• Ion Mobility Spectrometry
• Mass Spectrometry
• Ms-ms
• Surface-induced Dissociation
• Time-of-flight

Digital Object Identifier (DOI)

• 10.1016/j.ijms.2008.11.011

start page

• 39

end page

• 45

volume

• 287

issue

• 1-3

URL

• http://dx.doi.org/10.1016/j.ijms.2008.11.011