Label-free biosensing with lipid-functionalized gold nanorods. Academic Article

abstract

• The fabrication of a label-free mass spectrometry and optical detection-based biosensor platform for the detection of low-abundance lipophilic analytes in complex mixtures is described. The biosensor consists of a lipid layer partially tethered to the surface of a gold nanorod. The effectiveness of the biosensor is demonstrated for the label-free detection of a lipophilic drug in aqueous solution and a lipopeptide in serum.

authors

• Russell, David

published proceedings

• J Am Chem Soc

author list (cited authors)

• Castellana, E. T., Gamez, R. C., & Russell, D. H.

citation count

• 68

complete list of authors

• Castellana, Edward T||Gamez, Roberto C||Russell, David H

publication date

• March 2011

publisher

• American Chemical Society (ACS)  Publisher

published in

• Journal of the American Chemical Society  Journal

keywords

• Animals
• Biosensing Techniques
• Cattle
• Gold
• Lipids
• Mass Spectrometry
• Nanotubes
• Surface Properties

PubMed Central ID

• 21384858

Digital Object Identifier (DOI)

• 10.1021/ja109936h

start page

• 4182

end page

• 4185

volume

• 133

issue

• 12

URL

• http://dx.doi.org/10.1021/ja109936h