Label-free biosensing with lipid-functionalized gold nanorods. Academic Article uri icon


  • The fabrication of a label-free mass spectrometry and optical detection-based biosensor platform for the detection of low-abundance lipophilic analytes in complex mixtures is described. The biosensor consists of a lipid layer partially tethered to the surface of a gold nanorod. The effectiveness of the biosensor is demonstrated for the label-free detection of a lipophilic drug in aqueous solution and a lipopeptide in serum.

published proceedings

  • J Am Chem Soc

author list (cited authors)

  • Castellana, E. T., Gamez, R. C., & Russell, D. H.

citation count

  • 68

complete list of authors

  • Castellana, Edward T||Gamez, Roberto C||Russell, David H

publication date

  • March 2011