The multiplexed chemical kinetic photoionization mass spectrometer: a new approach to isomer-resolved chemical kinetics. Academic Article uri icon


  • We have developed a multiplexed time- and photon-energy-resolved photoionization mass spectrometer for the study of the kinetics and isomeric product branching of gas phase, neutral chemical reactions. The instrument utilizes a side-sampled flow tube reactor, continuously tunable synchrotron radiation for photoionization, a multimass double-focusing mass spectrometer with 100% duty cycle, and a time- and position-sensitive detector for single ion counting. This approach enables multiplexed, universal detection of molecules with high sensitivity and selectivity. In addition to measurement of rate coefficients as a function of temperature and pressure, different structural isomers can be distinguished based on their photoionization efficiency curves, providing a more detailed probe of reaction mechanisms. The multiplexed three-dimensional data structure (intensity as a function of molecular mass, reaction time, and photoionization energy) provides insights that might not be available in serial acquisition, as well as additional constraints on data interpretation.

published proceedings

  • Rev Sci Instrum

altmetric score

  • 3

author list (cited authors)

  • Osborn, D. L., Zou, P., Johnsen, H., Hayden, C. C., Taatjes, C. A., Knyazev, V. D., ... Leone, S. R.

citation count

  • 164

complete list of authors

  • Osborn, David L||Zou, Peng||Johnsen, Howard||Hayden, Carl C||Taatjes, Craig A||Knyazev, Vadim D||North, Simon W||Peterka, Darcy S||Ahmed, Musahid||Leone, Stephen R

publication date

  • October 2008