A genetically encoded boronate-containing amino acid.
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abstract
(Figure Presented) A biological boronate: An orthogonal tRNA/aminoacyl-tRNA synthetase pair has been evolved for the genetic incorporation of a boronic acid into proteins. This amino acid has been used to purify proteins in a one-step scarless purification procedure as well as for the site-specific labeling of proteins using various boronic acid chemistries. 2008 Wiley-VCH Verlag GmbH & Co. KGaA.