Time-of-flight flow imaging of two-component flow inside a microfluidic chip. Academic Article uri icon


  • Here we report on using NMR imaging and spectroscopy in conjunction with time-of-flight tracking to noninvasively tag and monitor nuclear spins as they flow through the channels of a microfluidic chip. Any species with resolvable chemical-shift signatures can be separately monitored in a single experiment, irrespective of the optical properties of the fluids, thereby eliminating the need for foreign tracers. This is demonstrated on a chip with a mixing geometry in which two fluids converge from separate channels, and is generally applicable to any microfluidic device through which fluid flows within the nuclear spin-lattice relaxation time.

author list (cited authors)

  • Harel, E., Hilty, C., Koen, K., McDonnell, E. E., & Pines, A

citation count

  • 34

complete list of authors

  • Harel, Elad||Hilty, Christian||Koen, Katherine||McDonnell, Erin E||Pines, Alex

publication date

  • January 2007