Flexible Zirconium Metal‐Organic Frameworks as Bioinspired Switchable Catalysts Academic Article uri icon


  • Flexible metal-organic frameworks (MOFs) are highly desirable in host-guest chemistry owing to their almost unlimited structural/functional diversities and stimuli-responsive pore architectures. Herein, we designed a flexible Zr-MOF system, namely PCN-700 series, for the realization of switchable catalysis in cycloaddition reactions of CO2 with epoxides. Their breathing behaviors were studied by successive single-crystal X-ray diffraction analyses. The breathing amplitudes of the PCN-700 series were modulated through pre-functionalization of organic linkers and post-synthetic linker installation. Experiments and molecular simulations confirm that the catalytic activities of the PCN-700 series can be switched on and off upon reversible structural transformation, which is reminiscent of sophisticated biological systems such as allosteric enzymes.

altmetric score

  • 11.35

author list (cited authors)

  • Yuan, S., Zou, L., Li, H., Chen, Y., Qin, J., Zhang, Q., ... Zhou, H.

citation count

  • 102

publication date

  • June 2016