Formation of the chromophore of the pyoverdine siderophores by an oxidative cascade. Academic Article uri icon


  • The pyoverdine chromophore is formed in a reaction involving a two-electron oxidation, a conjugate addition, and a second two-electron oxidation. This oxidative cascade can be carried out with polyphenol oxidase (PPO), MnO(2), and cell-free extracts from Pseudomonas aeruginosa. [reaction: see text]

published proceedings

  • Org Lett

author list (cited authors)

  • Dorrestein, P. C., Poole, K., & Begley, T. P.

citation count

  • 36

complete list of authors

  • Dorrestein, Pieter C||Poole, Keith||Begley, Tadhg P

publication date

  • June 2003