Oxidative cascades: a facile biosynthetic strategy for the assembly of complex molecules. Academic Article

abstract

• Electron-rich aromatic compounds undergo a facile tandem reaction sequence involving an iterative two-electron oxidation/aromatization. This review will describe the application of this motif to the synthesis of dimethylbenzimidazole, pyoverdine, actinomycin, cystodytin, pyrroloquinoline quinone, and the cataract pigment.

authors

• Begley, Tadhg

published proceedings

• Bioorg Chem

author list (cited authors)

• Dorrestein, P., & Begley, T. P.

citation count

• 16

complete list of authors

• Dorrestein, Pieter||Begley, Tadhg P

publication date

• January 2005

publisher

• Elsevier  Publisher

published in

• Bioorganic Chemistry  Journal

keywords

• Benzimidazoles
• Catalysis
• Dactinomycin
• ENZYMES
• Electrons
• Hydrocarbons, Aromatic
• Ligands
• Molecular Conformation
• Oligopeptides
• Oxidation-Reduction
• Pigments, Biological
• Quinones

Digital Object Identifier (DOI)

• 10.1016/j.bioorg.2004.06.006

start page

• 136

end page

• 148

volume

• 33

issue

• 3

URL

• http%3A%2F%2Fdx.doi.org%2F10.1016%2Fj.bioorg.2004.06.006