Characterization of two kinases involved in thiamine pyrophosphate and pyridoxal phosphate biosynthesis in Bacillus subtilis: 4-amino-5-hydroxymethyl-2methylpyrimidine kinase and pyridoxal kinase. Academic Article uri icon

abstract

  • Two Bacillus subtilis genes encoding two proteins (currently annotated ThiD and YjbV) were overexpressed and characterized. YjbV has 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase activity and should be reannotated ThiD, and B. subtilis ThiD has pyridoxine, pyridoxal, and pyridoxamine kinase activity and should be reannotated PdxK.

published proceedings

  • J Bacteriol

author list (cited authors)

  • Park, J., Burns, K., Kinsland, C., & Begley, T. P.

citation count

  • 43

complete list of authors

  • Park, Joo-Heon||Burns, Kristin||Kinsland, Cynthia||Begley, Tadhg P

publication date

  • February 2004