Biosynthesis of the Thioquinolobactin Siderophore: an Interesting Variation on Sulfur Transferâ–¿ Academic Article uri icon

abstract

  • The thioquinolobactin siderophore from Pseudomonas fluorescens ATCC 17400 utilizes a variation of the sulfur transfer chemistry found in thiamine and molydobterin biosynthesis. A JAMM motif protein cleaves the C-terminal amino acid residues following a diglycine moiety on a small sulfur carrier protein, and the modified C terminus is activated and sulfurylated, forming a thiocarboxylate.

author list (cited authors)

  • Godert, A. M., Jin, M. i., McLafferty, F. W., & Begley, T. P.

citation count

  • 41

publication date

  • April 2007