Identification of the Escherichia coli nicotinic acid mononucleotide adenylyltransferase gene. Academic Article uri icon

abstract

  • The gene (ybeN) coding for nicotinate mononucleotide adenylyltransferase, an NAD(P) biosynthetic enzyme, has been identified and overexpressed in Escherichia coli. This enzyme catalyzes the reversible adenylation of nicotinate mononucleotide and shows product inhibition. The rate of adenylation of nicotinate mononucleotide is at least 20 times faster than the rate of adenylation of nicotinamide mononucleotide.

published proceedings

  • J Bacteriol

altmetric score

  • 3

author list (cited authors)

  • Mehl, R. A., Kinsland, C., & Begley, T. P.

citation count

  • 38

complete list of authors

  • Mehl, RA||Kinsland, C||Begley, TP

publication date

  • August 2000