A NOVEL HETEROBIMETALLIC ASYMMETRIC HYDROGENATION CATALYST BASED UPON A CHIRAL RHENIUM TEMPLATE CONTAINING 2 PHOSPHIDO SUBSTITUENTS Academic Article uri icon

abstract

  • The Rhodiumrhenium complex 1 can be regarded as prototype of a new generation of hydrogenation catalysts. A salientcharacteristic is the coupling of an Rh1 centerknown to exhibit catalytic activity in hydrogenationswith a bis(diphenylphosphido) ligand, which contains a pseudotetrahedrally coordinated stereogenic Re atom in the skeletal framework. For example, acetamidoacrylic acid is hydrogenated in presence of 1 (0.4 mol% in THF) with 1 atm H2 at room temperature to (R)Nacetylalanine with 98% ee (yield: 82%). (Figure Presented.) Copyright 1987 by VCH Verlagsgesellschaft mbH, Germany

published proceedings

  • ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH

author list (cited authors)

  • ZWICK, B. D., ARIF, A. M., PATTON, A. T., & GLADYSZ, J. A.

citation count

  • 34

complete list of authors

  • ZWICK, BD||ARIF, AM||PATTON, AT||GLADYSZ, JA

publication date

  • September 1987

publisher