A quadruply-bonded dirhenium complex bridged by two N-1/N-6 adenate ligands Academic Article

abstract

• The first structurally characterized example of a metal-metal bonded complex bridged by the DNA nucleobase adenine through the N1, N6 positions is reported. The new dirhenium compound, Re2(O2CCH2CH3) 2(9-EtA)2Cl2CH3CH 2OC6H14, binds to adenine at the sites where thymine normally engages in Watson-Crick base-pairing. Such chemistry, if it occurs in vivo, could play a role in the carcinostatic activity of tetrapropionatodirhenium complexes that are known to inhibit DNA replication. 1998 Elsevier Science S.A. All rights reserved.

authors

• Dunbar, Kim

published proceedings

• INORGANIC CHEMISTRY COMMUNICATIONS

author list (cited authors)

• Prater, M. E., Mindiola, D. J., Ouyang, X., & Dunbar, K. R.

citation count

• 24

complete list of authors

• Prater, ME||Mindiola, DJ||Ouyang, X||Dunbar, KR

publication date

• December 1998

publisher

• Elsevier  Publisher

published in

• Inorganic Chemistry Communications  Journal

keywords

• Adenate Ligands
• Crystal Structures
• Rhenium Complexes

Digital Object Identifier (DOI)

• 10.1016/S1387-7003(98)00127-0

start page

• 475

end page

• 477

volume

• 1

issue

• 12

URL

• http%3A%2F%2Fdx.doi.org%2F10.1016%2Fs1387-7003%2898%2900127-0