Resin-bound models of the [FeFe]-hydrogenase enzyme active site and studies of their reactivity. Academic Article uri icon

abstract

  • The immobilization of synthetic analogues of the [FeFe]-hydrogenase, [FeFe]H(2)ase, enzyme active site on polyethyleneglycol-rich polystyrene beads is described. Using the reactivity of the amine termini of the PEG chains with carboxylates incorporated into (mu-SRS)[Fe(CO)(3)](2) or (mu-SR)(2)[Fe(CO)(3)](2) derivative, nu(CO)IR signatures can be used to interrogate the structure and properties of the diiron carbonyl complexes once incorporated into the PEG environment of the polymer beads. Alternatively, the SRS dithiolate was first attached to the resin and the diiron unit assembled via an in situ process on the bead.

published proceedings

  • Dalton Trans

author list (cited authors)

  • Green, K. N., Hess, J. L., Thomas, C. M., & Darensbourg, M. Y.

citation count

  • 26

complete list of authors

  • Green, Kayla N||Hess, Jennifer L||Thomas, Christine M||Darensbourg, Marcetta Y

publication date

  • June 2009