Imidazole-containing (N3S)-Ni(II) complexes relating to nickel containing biomolecules. Academic Article uri icon


  • Dimeric (N(2)S)Ni complexes and the monomeric N(2)S(2) bismercaptodiazacycloheptane nickel complex, (bme-dach)Ni, serve as precursors to two N(2)-, N'-/ S- complexes where N(2) = diazacycloheptane, N' = imidazole and S = thiolate. As rare examples of nickel complexes containing a mixed thiolate/imidazole ligand set, these complexes are characterized by X-ray diffraction, UV/vis, and variable temperature (1)H NMR spectroscopies, and electrochemistry. Density functional theory computations relate the orientation of the imidazole with respect to the N(2)N'SNi square plane to the VT NMR observed fluxionality and activation parameters. The superoxide dismutase activity of the imidazole complexes was investigated by the nitroblue tetrazolium assay.

published proceedings

  • Inorg Chem

author list (cited authors)

  • Jenkins, R. M., Singleton, M. L., Almaraz, E., Reibenspies, J. H., & Darensbourg, M. Y.

citation count

  • 43

complete list of authors

  • Jenkins, Roxanne M||Singleton, Michael L||Almaraz, Elky||Reibenspies, Joseph H||Darensbourg, Marcetta Y

publication date

  • August 2009