Notizen. Die Metallierung von N,N,N′,N′‐Tetramethylethylendiamin (TMEDA)
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The Metalation of N,N,N′,N′,‐Tetramethylethylenediamine (TMEDA) TMEDA may be metalated with good regioselectivity: tert‐BuLi attacks preferably a methyl group whereas a methylene group is deprotonated by n‐BuLi/tert‐BuOK. Thus, trapping with Me3SnCl and hydrolytic work‐up give either 53% of Me2N[CH2]2NMe(CH2SnMe3) (2) and 5% of (Me3Sn)(Me2N)CCH2 (3) or 3 alone (42%), respectively. 3 is formed from deprotonated TMEDA by elimination of amide which can be trapped as Me2N(SnMe3) (5); some trans‐(Me3Sn)CHCH(NMe2) (4) is also obtained. The structures of the compounds follow mainly from 1H‐, 13C‐, 15N‐, and 119Sn‐NMR data. Copyright © 1987 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
author list (cited authors)
Köhler, F. H., Hertkorn, N., & Blümel, J.