A microchannel-confined surface-initiated atom transfer radical polymerization was described. A microchannel was formed by placing a patterned poly(dimethylsiloxane) (PDMS) stamp onto an initiator-functionalized self-assembled monolayer on a silicon wafer. A channel was placed on the surface and quickly filled with the polymerization mixture to evaluate the polymerization behavior of the surface after contact with PDMS and the reinitiation efficiency of the grafted layer. It was shown that surface-initiated atom transfer] radical polymerization can be carried out inside microchannels to produce flat gradient and patterned surfaces.
