CHANGES IN FUNCTIONING WITH GLYCOSAMINOGLYCAN POLYSULFATE IN PRIMARY DEGENERATIVE AND MULTIINFARCT DEMENTIA uri icon

abstract

  • In a multicenter clinical trial two dosages of glycosaminoglycan polysulfate were compared in patients with primary degenerative dementia (PDD) and multi-infarct dementia (MID). There was significant improvement on the Plutchik Geriatric Scale in total score and three of the five factor scores (ie, social dysfunction, incapacitation, and work performance) in the PDD group with the investigational drug. There was significantly greater improvement in social dysfunction and sensory impairment with higher doses.

published proceedings

  • CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL

author list (cited authors)

  • BAN, T. A., CONTI, L., MOREY, L., LAZZERINI, F., CORNELLI, U., POSTIGLIONE, A., & GROSSI, D.

complete list of authors

  • BAN, TA||CONTI, L||MOREY, L||LAZZERINI, F||CORNELLI, U||POSTIGLIONE, A||GROSSI, D

publication date

  • January 1987