GLOBAL CHANGES WITH GLYCOSAMINOGLYCAN POLYSULFATE IN PRIMARY DEGENERATIVE AND MULTIINFARCT DEMENTIA

abstract

• In a multicenter clinical trial two dosages of glycosaminoglycan polysulfate were compared in patients with primary degenerative dementia and multi-infarct dementia. There was an improvement in patients on glycosaminoglycan polysulfate on all the three items of the Clinical Global Impressions Scale, while the difference in improvement between the two dosage groups did not reach the accepted level of statistical significance. Global improvement and the improvement in severity of illness were significantly greater in the diagnostic group with primary degenerative dementia than in the diagnostic group with multi-infarct dementia. The same applies to the efficacy index on which the primary degenerative dementia group fared significantly better than the multi-infarct dementia group.

authors

• Morey, Leslie

published proceedings

• CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL

author list (cited authors)

• BAN, T. A., MODAFFERI, A., MOREY, L., PLACIDI, G. F., POSTIGLIONE, A., RE, F., & SANTINI, V.

complete list of authors

• BAN, TA||MODAFFERI, A||MOREY, L||PLACIDI, GF||POSTIGLIONE, A||RE, F||SANTINI, V

publication date

• January 1987

published in

• Current Therapeutic Research: clinical and experimental  Journal

start page

• 631

end page

• 636

volume

• 41

issue

• 5