Chemical constituents of Abies nukiangensis. Academic Article uri icon

abstract

  • During a survey on chemical constituents of Abies nukiangensis, seven previously unreported compounds, including six triterpenes (1-6) and one phenol (7) were isolated and characterized, together with 37 known miscellaneous chemical constituents. The structures of compounds 1-7 were established mainly by extensive analysis of the 1D and 2D NMR, as well as HRMS data. The absolute configurations of compounds 1 and 8 were confirmed unambiguously by the Cu-K X-ray crystallography. Compounds 3 and 8-10 showed significant anti-hepatitis C virus effects with EC50 values of 3.73, 2.67, 1.33 and 2.25M, respectively.

published proceedings

  • Phytochemistry

author list (cited authors)

  • Li, Y., Gao, Y., Jin, H., Shan, L., Liang, X., Xu, X., ... Zhang, W.

citation count

  • 10

complete list of authors

  • Li, Yong-Li||Gao, Yan-Xia||Jin, Hui-Zi||Shan, Lei||Liang, Xue-Song||Xu, Xi-Ke||Yang, Xian-Wen||Wang, Ning||Steinmetz, Andre||Chen, Zhilei||Zhang, Wei-Dong

publication date

  • October 2014