High‐speed photoacoustic microscopy of mouse cortical microhemodynamics
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We applied high-speed photoacoustic microscopy (PAM) for both cortical microenvironment studies and dynamic brain studies, with micrometer-level optical resolution and a millisecond-level cross-sectional imaging speed over a millimeter-level field of view. We monitored blood flow redistribution in mini-stroke mouse models and cerebral autoregulation induced by a vasoactive agent. Our results collectively suggest that high-speed PAM is a promising tool for understanding dynamic neurophysiological phenomena, complementing conventional imaging modalities.
author list (cited authors)
Lin, L. i., Yao, J., Zhang, R., Chen, C., Huang, C., Li, Y., ... Wang, L. V.