Experimental obesity syndromes in rats: influence of diet palatability on maintenace body weights. Academic Article

abstract

• Female rats with ventromedial hypothalamic (VMH) lesions, parasagittal hypothalamic knife cuts (KC), or dorsolateral tegmental (DLT) lesions were maintained successively on 0.2 and 0.4% quinine chow, plain chow, pellets, wet mash, and high fat diets (15-45 days each). Only VMH rats overate the 0.2% quinine diet and only KC rats underate the 0.4% quinine diet. Although DLT rats did not overeat the unadulterated chow and pellet diets, as did VMH and KC rats, all three surgical groups attained roughly comparable elevated body weight means after access to the wet mash and high fat diets. Thus, dietary manipulations clearly induce differential patterns of feeding behavior in these three obesity syndromes. 1979.

authors

• Wellman, Paul

published proceedings

• Physiol Behav

author list (cited authors)

• Peters, R. H., Wellman, P. J., & Gunion, M. W.

citation count

• 9

complete list of authors

• Peters, RH||Wellman, PJ||Gunion, MW

publication date

• January 1979

publisher

• Elsevier  Publisher

published in

• Physiology and Behavior  Journal

keywords

• Animals
• Body Weight
• Choice Behavior
• Eating
• Female
• Hypothalamus
• Hypothalamus, Middle
• Norepinephrine
• Obesity
• Quinine
• Rats
• Taste
• Tegmentum Mesencephali

Digital Object Identifier (DOI)

• 10.1016/0031-9384(79)90162-8

start page

• 693

end page

• 699

volume

• 23

issue

• 4

URL

• http%3A%2F%2Fdx.doi.org%2F10.1016%2F0031-9384%2879%2990162-8