High versus low pressure receptors in modulating the volumetric control of antidiuretic hormone secretion in the monkey.
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abstract
Experiments were carried out in six Macaca fascicularis monkeys to determine the relationships between arterial pressure (AP) and plasma arginine vasopressin (AVP) and left ventricular enddiastolic pressure (LVEDP) and plasma AVP in response to a two-step hemorrhage. In response to each hemorrhage, there occurred a significant decline in AP, a significant elevation of plasma AVP and variable but nonsignificant changes in LVEDP. These results are consistent with the hypothesis that in the primate high pressure receptors are more important than low pressure receptors in the volumetric control of AVP secretion. 1982 Dr. Dietrich Steinkopff Verlag.