selected publications academic article Case, E., Mahapatra, S., Hoffpauir, C. T., Konganti, K., Hillhouse, A. E., Samuel, J. E., & Van Schaik, E. J. (2022). Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii. Microbiology spectrum. 10(4), e0248421-e02421. Zhang, Y., Fu, J., Liu, S., Wang, L., Qiu, J., van Schaik, E. J., ... Luo, Z. (2022). Coxiella burnetii inhibits host immunity by a protein phosphatase adapted from glycolysis. Proceedings of the National Academy of Sciences of the United States of America. 119(1), e2110877119. Yang, J., Eslami, M., Chen, Y., Das, M., Zhang, D., Chen, S., ... de Figueiredo, P. (2022). Phenotype-Based Threat Assessment. Proceedings of the National Academy of Sciences of the United States of America. 119(14), e2112886119. Fratzke, A. P., van Schaik, E. J., & Samuel, J. E. (2022). Immunogenicity and Reactogenicity in Q Fever Vaccine Development. Frontiers in Immunology. 13, 886810. Siadous, F. A., Cantet, F., Van Schaik, E., Burette, M., Allombert, J., Lakhani, A., ... Martinez, E. (2021). Coxiella effector protein CvpF subverts RAB26-dependent autophagy to promote vacuole biogenesis and virulence. Autophagy. 17(3), 706-722. Gregory, A. E., van Schaik, E. J., Fratzke, A. P., Russell-Lodrigue, K. E., Farris, C. M., & Samuel, J. E. (2021). Soluble antigens derived from Coxiella burnetii elicit protective immunity in three animal models without inducing hypersensitivity. Cell Reports Medicine. 2(12), 100461-100461. Fratzke, A. P., Gregory, A. E., van Schaik, E. J., & Samuel, J. E. (2021). Coxiella burnetii Whole Cell Vaccine Produces a Th1 Delayed-Type Hypersensitivity Response in a Novel Sensitized Mouse Model. Frontiers in Immunology. 12, 754712. Gregory, A. E., van Schaik, E. J., Russell-Lodrigue, K. E., Fratzke, A. P., & Samuel, J. E. (2019). Coxiella burnetii Intratracheal Aerosol Infection Model in Mice, Guinea Pigs, and Nonhuman Primates. Infection and Immunity. 87(12), e00178-e00119. Chen, C., van Schaik, E. J., Gregory, A. E., Vigil, A., Felgner, P. L., Hendrix, L. R., Faris, R., & Samuel, J. E. (2019). Chemokine Receptor 7 Is Essential for Coxiella burnetii Whole-Cell Vaccine-Induced Cellular Immunity but Dispensable for Vaccine-Mediated Protective Immunity. Journal of Infectious Diseases. 220(4), 624-634. Weber, M. M., Faris, R., van Schaik, E. J., & Samuel, J. E. (2018). Identification and characterization of arginine finger-like motifs, and endosome-lysosome basolateral sorting signals within the Coxiella burnetii type IV secreted effector protein CirA. Microbes and Infection. 20(5), 302-307. Pandey, A., Ding, S. L., Qin, Q., Gupta, R., Gomez, G., Lin, F., ... de Figueiredo, P. (2017). Global Reprogramming of Host Kinase Signaling in Response to Fungal Infection. Cell Host and Microbe. 21(5), 637-649.e6. van Schaik, E. J., Case, E. D., Martinez, E., Bonazzi, M., & Samuel, J. E. (2017). The SCID Mouse Model for Identifying Virulence Determinants in Coxiella burnetii. Frontiers in Cellular and Infection Microbiology. 7(FEB), 25. Weber, M. M., Faris, R., van Schaik, E. J., McLachlan, J. T., Wright, W. U., Tellez, A., ... Samuel, J. E. (2016). The Type IV Secretion System Effector Protein CirA Stimulates the GTPase Activity of RhoA and Is Required for Virulence in a Mouse Model of Coxiella burnetii Infection. 84(9), 2524-2533. Soltysiak, K. A., van Schaik, E. J., & Samuel, J. E. (2015). Surfactant Protein D Binds to Coxiella burnetii and Results in a Decrease in Interactions with Murine Alveolar Macrophages. PLoS ONE. 10(9), e0136699-e0136699. van Schaik, E. J., Chen, C., Mertens, K., Weber, M. M., & Samuel, J. E. (2013). Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii. Nature Reviews Microbiology. 11(8), 561-573. van Schaik, E. J., & Samuel, J. E. (2012). Phylogenetic diversity, virulence and comparative genomics. Advances in Experimental Medicine and Biology. 984, 13-38. van Schaik, E. J., Tom, M., & Woods, D. E. (2009). Burkholderia pseudomallei isocitrate lyase is a persistence factor in pulmonary melioidosis: implications for the development of isocitrate lyase inhibitors as novel antimicrobials. Infection and Immunity. 77(10), 4275-4283. van Schaik, E., Tom, M., DeVinney, R., & Woods, D. E. (2008). Development of novel animal infection models for the study of acute and chronic Burkholderia pseudomallei pulmonary infections. Microbes and Infection. 10(12-13), 1291-1299. Yu, B., Giltner, C. L., Van Schaik, E. J., Bautista, D. L., Hodges, R. S., Audette, G. F., Li, D. Y., & Irvin, R. T. (2007). A Novel Biometallic Interface: High Affinity Tip-AssociatedBinding by Pilin-Derived Protein Nanotubes. Journal of Bionanoscience. 1(2), 73-83. Giltner, C. L., Van Schaik, E. J., Audette, G. F., Kao, D., Hodges, R. S., Hassett, D. J., & Irvin, R. T. (2006). The Pseudomonas aeruginosa type IV pilin receptor binding domain functions as an adhesin for both biotic and abiotic surfaces. Molecular Microbiology. 60(3), 813-813. Giltner, C. L., van Schaik, E. J., Audette, G. F., Kao, D., Hodges, R. S., Hassett, D. J., & Irvin, R. T. (2006). The Pseudomonas aeruginosa type IV pilin receptor binding domain functions as an adhesin for both biotic and abiotic surfaces. Molecular Microbiology. 59(4), 1083-1096. van Schaik, E. J., Giltner, C. L., Audette, G. F., Keizer, D. W., Bautista, D. L., Slupsky, C. M., Sykes, B. D., & Irvin, R. T. (2005). DNA binding: a novel function of Pseudomonas aeruginosa type IV pili. Journal of Bacteriology. 187(4), 1455-1464. Audette, G. F., van Schaik, E. J., Hazes, B., & Irvin, R. T. (2005). DNA-Binding Protein Nanotubes: Learning from Nature's Nanotech Examples. Nano Letters. 5(1), 201-201. Audette, G. F., van Schaik, E. J., Hazes, B., & Irvin, R. T. (2004). DNA-Binding Protein Nanotubes: Learning from Nature's Nanotech Examples. Nano Letters. 4(10), 1897-1902. Hensel, M. E., Chaki, S. P., Stranahan, L., Gregory, A. E., van Schaik, E. J., Garcia-Gonzalez, D. G., ... Arenas-Gamboa, A. M. Intratracheal Inoculation with Brucella melitensis in the Pregnant Guinea Pig Is an Improved Model for Reproductive Pathogenesis and Vaccine Studies. Infection and Immunity. 88(10), 10.1128/iai.00204-10.1128/iai.00220. chapter van Schaik, E. J., Gregory, A. E., Audette, G. F., & Samuel, J. E. (2018). Nanovaccines against Intracellular Pathogens Using Coxiella burnetii as a Model Organism. IMMUNE ASPECTS OF BIOPHARMACEUTICALS AND NANOMEDICINES. (pp. 507-535). Taylor & Francis. conference paper Ward, L. R., Van Schaik, E., Samuel, J., & Pillai, S. D. (2020). Reduction in microbial infection risks from raw milk by Electron Beam Technology. Radiation Physics and Chemistry: the journal for radiation physics, radiation chemistry and radiation processing. 108567-108567.